When monitors agree, and when they disagree
Ten clinical scenarios where two or three modalities tell different stories. Walk through the discordance, learn the heuristics, then try the decision points.
- 1Scenario
PRx vs COx discordance in TBI
TBI patient: PRx says intact, COx says impaired. Why?
prx · cox · nirs - 2Scenario
TCD vs ICP, pediatric SAH day 6
SAH child day 6: ICP normal, TCD velocity climbing. What now?
tcd · icp - 3Scenario
aEEG narrowing + TCD systolic peaks
Sedated TBI: aEEG narrowing + TCD systolic peaks, what is happening?
eeg · aeeg · tcd - 4Scenario
A 4-hour CPPopt loop, COGiTATE-style
Walk through the 4-hour CPPopt computation and how to act on the orange band.
cppopt · prx · cpp - 5Scenario
HTS bolus, ICP falls, watch the NIRS
Hypertonic saline bolus: ICP falls, but does the NIRS over- or under-shoot?
icp · nirs · cpp - 6Scenario
MNM on VA-ECMO
VA-ECMO patient: PRx unreliable; what do you trust?
nirs · eeg · pupillometry · tcd - 7Scenario
MNM contributions to brain-death evaluation
Use of TCD, evoked potentials, and pupillometry alongside the clinical exam.
tcd · evoked-potentials · pupillometry · clinical-exam - 8Scenario
When monitor X disagrees with monitor Y
A bedside flowchart for the most common discordances and what to check first.
icp · prx · tcd · nirs · eeg - 9Scenario
BOOST-style PbtO₂-targeted CPP and FiO₂
PbtO₂ < 18 mmHg, walk the CPP/FiO₂ titration tree.
pbto2 · cpp · icp - 10Scenario
HIE in a 2-day-old: aEEG, NIRS, pupillometry
Cooling protocol day 2: integrate aEEG continuity, NIRS rSO₂, and pupillometry.
aeeg · nirs · pupillometry - 11Scenario
DKA cerebral oedema, Asher, 9y
New DKA, severe acidosis. Hour 4 of fluids: GCS drops, irritable, headache. What is your monitoring plan?
clinical-exam · pupillometry · onsd · nirs - 12Scenario
Refractory status epilepticus, Noah, 5y
Convulsive SE → refractory → super-refractory. The cEEG-guided sedation pathway, with multimodal sentinels.
eeg · aeeg · pupillometry · nirs - 13Scenario
When the kit isn't there, Amani, 3y
PICU at a regional hospital: ICP probe not available, no continuous EEG. What you can still do, and how.
clinical-exam · pupillometry · onsd · nirs · tcd - 14Scenario
Pediatric AIS, Maya, 8y
Sudden hemiparesis at school. Door-to-needle in the pediatric ED, hyperacute monitoring, and the role of NIRS / TCD / cEEG.
clinical-exam · tcd · nirs · eeg · pupillometry - 15Scenario
Bacterial meningitis with raised ICP, Idris, 4y
Pediatric pneumococcal meningitis, day 2: GCS falling, irritability, suspected raised ICP. The neuromonitoring response.
clinical-exam · pupillometry · onsd · icp · nirs · eeg - 16Scenario
WLST and DCD pathway, Aliyah, 13y
After brain-death determination cannot be completed (residual cranial-nerve reflex), the family considers DCD. The role of MNM in supporting the conversation and the protocol.
clinical-exam · pupillometry · tcd · evoked-potentials - 17Scenario
Translating MNM for families, three conversations
Three real conversations: explaining a "PRx +0.32 trend" to a parent, communicating prognostic uncertainty in HIE, and the post-arrest "what does this number mean for my child" question.
clinical-exam - 18Scenario
Mitochondrial encephalopathy, Rafa, 18mo
Acute encephalopathy in a child with known POLG mutation. Why microdialysis L/P thresholds, MRI patterns, and clinical exam diverge from the textbook TBI playbook.
microdialysis · eeg · clinical-exam · nirs